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Episulin has been standardized in term of "Epicatechin", an active
principal of this formulation. After proper selection of the herbs, each and every herb is subjected to the rigid standards like assessment of foreign organic matter, water-soluble extractive, and ethanol soluble extractive, moisture content, microbial contamination and chromatographic finger printing. After quality assessment of each and every ingredient, they have to undergo processing. Processing of the herb and active ingredient involve proprietary know-how. In Episulin the active ingredient has been extracted, processed, concentrated by a unique technique so that the goodness of whole constituent is incorporated in one capsule. After successfully developing the combination (formulation), Episulin was standardized in term of moisture content, total extractable component, foreign and inorganic impurities, total microbial load, active principle 'Epicatechin'; disintegration time, weight variation of the capsule etc. To make the consistency of the formulation (which is the major problem in herbal formulation) 'finger printing' of the formulation has been developed in term of specific marker, which is the 'key' of the formulation. Apart from this .the formulation has also been tested in terms of its 'efficacy' under different stressed conditions. Episulin has also undergone toxicological evaluation at I.T.R.C., Institute of Toxicological Research Centre, Lucknow for acute toxicity studies and has been found totally free from any side effects. |
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